Mestrado em Assistência Farmacêutica

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Navegando Mestrado em Assistência Farmacêutica por Assunto "Assistência Farmacêutica"

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    Avaliação do impacto do acompanhamento farmacoterapêutico a pessoas com hipertensão arterial em um município sul-capixaba : ensaio clínico pragmático
    (Universidade Federal do Espírito Santo, 2024-03-15) Alencar, Taiana de; Co-orientador1; https://orcid.org/; http://lattes.cnpq.br/; Co-orientador2; https://orcid.org/; http://lattes.cnpq.br/; Santos Júnior, Genival Araujo dos ; https://orcid.org/; http://lattes.cnpq.br/; Orientador2; https://orcid.org/; http://lattes.cnpq.br/; https://orcid.org/; http://lattes.cnpq.br/; Oliveira Filho, Alfredo Dias de; dc.contributor.referee1ID; http://lattes.cnpq.br/; Severi, Juliana Aparecida; https://orcid.org/; http://lattes.cnpq.br/; Silva, Rafaella de Oliveira Santos; https://orcid.org/; http://lattes.cnpq.br/; 4º membro da banca; https://orcid.org/; http://lattes.cnpq.br/; 5º membro da banca; https://orcid.org/; http://lattes.cnpq.br/; 6º membro da banca; https://orcid.org/; http://lattes.cnpq.br/; 7º membro da banca; https://orcid.org/; http://lattes.cnpq.br/
    Introduction: Arterial hypertension (AH) is a chronic health condition that may require changes in lifestyle and the use of medication. However, this use is not without risks. In this context, the Pharmacotherapeutic Follow-up Service (FHS) has emerged as a strategy capable of improving the health outcomes of people with AH. However, there are few high-research studies on this subject. Objective: To assess the impact of FAS on the health outcomes of patients with AH in the health care network in the municipality of Alegre/ES. Method: This is an experimental single-blind randomized controlled clinical trial. People with hypertension who met the eligibility criteria (over 18 years of age, with self-reported hypertension, taking medication for hypertension for at least 6 months) were randomized in a 1:1 ratio to the intervention and control groups. They received FAS and usual care, respectively, for a period of 12 months. The study was conducted in the Health Care Network of the municipality of Alegre, Espírito Santo, Brazil, from January 2022 to November 2023. In both groups, primary outcomes (blood pressure and quality of life) and secondary outcomes (knowledge about hypertension, anthropometric profile and clinical examinations) were assessed at three points in time, six months apart. Ethical considerations were observed (CAAE registration number 13586319.6.0000.8151 | Opinion no. 4.732.878). Results: 128 patients were allocated to the intervention group (64) and the control group (64). Statistically significant differences were observed in the intra-group analysis in the intervention group, including SBP (∆ = -9.47 mmHg, p = 0.014), Total Cholesterol (∆ = -18.93 mg/dL, p = 0.001), LDL (∆ = -15.70 mg/dL, p < 0.001), non-HDL cholesterol (∆ = -19.76 mg/dL, p < 0.001) and cardiovascular risk (∆ = -1.82 points, p < 0.001). There was an increase in the score for knowledge about hypertension (∆ = 1.39 points, p < 0.001), an improvement in quality of life in the mental state subdimension (∆ = -2.76 points, p = 0.020) and somatic manifestations (∆ = -1.5 points, p = 0.012). In the control group, it was possible to observe an increase in the score for knowledge about hypertension (∆ = 1.52 points, p = 0.001) and an improvement in the VAS of the EQ5D (∆ = 10.33 points, p = 0.067). In addition, almost all the patients were satisfied or very satisfied with the service provided by the pharmacists. Conclusion: The results show a promising positive impact of FAS on clinical and humanistic parameters, as well as a reduction in cardiovascular risk for negative events over the next ten years. This study was registered with The Brazilian Clinical Trials Registry (ReBEC) under registration number: RBR-4c53f3m
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    Perfil clínico e humanístico de pacientes com hipertensão arterial da Rede de Atenção à Saúde de um município no Sul-Capixaba
    (Universidade Federal do Espírito Santo, 2023-08-11) Mendes, Mayra Cardozo; Santos Júnior, Genival Araujo dos; https://orcid.org/0000000256181846; http://lattes.cnpq.br/5917097187533724; https://orcid.org/0009-0003-4358-6603; http://lattes.cnpq.br/6949871999044526; Santana, Rafael Santos; https://orcid.org/0000-0003-4481-210X; http://lattes.cnpq.br/6970798378260844; Santos, Sabrina Cerqueira; https://orcid.org/0000-0001-6748-727X; http://lattes.cnpq.br/8757541282986479
    Introdução. Hypertension is the most prevalent chronic condition in primary care and the leading preventable cause of cardiovascular death worldwide. However, information about the clinical and humanistic profile of individuals with hypertension treated in a municipality in southern Espírito Santo, Brazil, is limited. Objective. To characterize the clinical and humanistic profile of patients with Arterial Hypertension within the healthcare network of a municipality in southern Espírito Santo. Method. A descriptive cross-sectional study with a quantitative approach conducted between January 2022 and July 2022 in the municipality of Alegre-ES. Study participants were individuals over 18 years of age, diagnosed with hypertension, and using at least one medication for hypertension. Data collection was performed using a structured form created by the author. Sociodemographic data, anthropometric profile, lifestyle, clinical profile, and pharmacotherapeutic profile were collected. Adherence to pharmacotherapy, knowledge about hypertension, overall quality of life, and quality of life related to hypertension were assessed using validated questionnaires. The study was approved by the Ethics Committee of the Federal University of Espírito Santo (CAAE: 13586319.6.0000.8151). Data were presented using descriptive statistics. Results: The study included 129 participants, of whom 74.41% (n=96) were women, with an average age of 59.83 ± 11.15 years, married (58.13%; n=75), self-identified as non-white (73.64%; n=95), did not engage in physical activity (75.2%; n=97), denied alcohol consumption (80.6%; n=104) and nicotine use (60.5%; n=78), and reported having two or more health conditions (69.76%; n=90). Women had an average weight of 75.16 ± 14.24 kg, and men had an average weight of 77.86 ± 13.79 kg. In clinical data, the lipid profile showed that 47.29% (n=61) had total cholesterol and 48.84% (n=63) had triglycerides above recommended levels. Regarding blood pressure, 34.89% (n=45) had systolic blood pressure greater than 140 mmHg, and 25.58% (n=33) had diastolic blood pressure greater than 90 mmHg. The majority were on polypharmacy (58.91%; n=76), and treatment adherence was considered high in 86.82% (n=123) of evaluated patients. Furthermore, 50.38% (n=65) had good knowledge about hypertension, and 68.22% (n=88) stated that hypertension does not influence their quality of life. Conclusion. Most participants exhibited clinical profiles in line with guidelines and clinical protocols, as well as positive results for the humanistic profile, potentially contributing to future studies.