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Documentos Administrativos Documentos administrativos da UFES (Relatórios institucionais, Atos normativos, Resoluções, Portarias e etc)Livros Digitais Livros digitais "ebooks" (e-livros) publicados ou adquiridos pela UFESProdução Científica Produção científica e técnica da UFES, como Artigos, livros e capítulos, trabalhos apresentados em eventos, entrevistas, resenhas, traduções, patentes, cultivares, marcas, etc.Teses e Dissertações Teses e dissertações depositadas no repositório da UFESTrabalhos Acadêmicos Trabalhos acadêmicos de conclusão de curso (TCC) de graduação e pós-graduação lato sensu
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Resolução/Cepe/Ufes/nº 127, de 4 de julho de 2025
(2025-07-04) Conselho de Ensino, Pesquisa e Extensão
Estabelece as normas que regulamentam a extensão na Universidade Federal do Espírito Santo.
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Nanoemulsão estabilizada com quitosana modificada e nanocelulose aplicadas na recuperação avançada de petróleo
(Universidade Federal do Espírito Santo, 2025-04-01) Pinto, Roberta Tristão; Nascimento, Andreas; https://orcid.org/0000-0002-4465-5450; http://lattes.cnpq.br/2072155247986639; Lacerda Júnior, Valdemar; https://orcid.org/0000-0002-8257-5443; http://lattes.cnpq.br/9819471276433138; https://orcid.org/0000-0002-7031-9813; http://lattes.cnpq.br/4067639048997633; Cunha Neto, Álvaro; https://orcid.org/0000-0002-1814-6214; http://lattes.cnpq.br/7448379486432052; Queiroz, Vagner Tebaldi de; https://orcid.org/0000-0002-8170-125X; http://lattes.cnpq.br/9963384168622230; Santos, Luiz Carlos Lobato dos; https://orcid.org/0000-0003-3824-7802; http://lattes.cnpq.br/8891045064075199; Araújo, Lorraine Louise Greco Cavalcanti de; https://orcid.org/0000-0003-3824-7802; http://lattes.cnpq.br/8891045064075199
In the current scenario of petroleum reserve depletion, chemical injection is a vital technique for enhanced oil recovery (EOR). This article presents an approach for developing an oil recovery fluid through experimental investigations and mechanistic descriptions of nanoemulsified systems. The nanoemulsions were stabilized by a cationic surfactant, cetyltrimethylammonium bromide (CTAB), an anionic amphiphilic polymer synthesized from chitosan (NaP-CMQ), and cellulose nanoparticles (CNC) extracted from banana pseudostem. The utilized compounds underwent comprehensive characterization. The physicochemical properties of the nanoemulsions include surface tension, pH, conductivity, droplet size (DLS), zeta potential, rheological behavior, phase behavior, IFT, wettability, and miscibility with crude oil. DLS results confirmed the formation of nanometric oil droplets (<500 nm) in the nanoemulsion phase for all systems. Nanoemulsions stabilized with polymer and surfactant were more efficient in reducing IFT (1.88 mN/m), while nanoemulsions stabilized with polymer/surfactant and nanoparticles promoted greater wettability alteration (19°). Rheological experiments demonstrated pseudoplastic behavior of the nanoemulsions through the adjustment of flow parameters using the power-law model. Crude oil emulsification studies revealed favorable miscibility with crude oil at 70°C, with synergistic interactions between polymer, surfactant, and nanoparticle. The recovery factor was 48.1 % of the original oil in place (OOIP) for the nanoemulsion stabilized with NaP-CMQ+CTAB+CNC. In summary, the developed nanoemulsion-based systems exhibit promising physicochemical and stabilization characteristics for EOR applications
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Pesquisa de bactérias resistentes aos antimicrobianos em duas localidades do Estado do Espírito Santo
(Universidade Federal do Espírito Santo, 2025-02-27) Mothé, Davi Abreu Carvalho; Santos, Kênia Valéria dos; https://orcid.org/0000-0001-6871-3128; http://lattes.cnpq.br/9074173162086323; http://lattes.cnpq.br/8506942685475849; Apolônio, Ana Carolina Morais; https://orcid.org/0000-0001-9049-7660; http://lattes.cnpq.br/7570808562726658; Resende, Juliana Alves; https://orcid.org/0000-0002-5476-3754; http://lattes.cnpq.br/8223821041049149
Antimicrobial resistance (AMR) is a growing concern, especially due to the spread of resistant bacteria in the environment, which can act as a reservoir for resistance genes. Vitória Bay and the Caramuru district in Espírito Santo, Brazil, stand out as hotspots for the study of AMR. The former because of the intense port activity and high flow of people and goods, and the latter because of agricultural and poultry production with intensive use of antimicrobials. Selective antimicrobial media were used to screen for the presence of antimicrobial-resistant bacteria in water samples from Vitória Bay and in environmental samples from the Caramuru district: water, soil, poultry litter, wet bathroom surfaces, animal feces and flies. In Caramuru, 138 isolates were identified with a predominance of Escherichia coli and Enterobacter, while in Vitória Bay, 50 isolates were identified with a predominance of pathogens such as Klebsiella pneumoniae and Acinetobacter pittii. Among the Gram-positive cocci, only Enterococcus spp. were found, one of which was resistant to vancomycin in Vitória Bay. Phenotypic tests confirmed the presence of multidrug-resistant isolates in different environmental sources, with extended-spectrum beta-lactamase (ESBL) production more frequent in Vitória Bay. The production of metallo-beta-lactamases was observed in Enterobacter spp. in Caramuru and in K. pneumoniae in Vitória Bay, while resistance to polymyxin B was observed in E. asburiae, E. cloacae, E. coli, A. baumannii and P. aeruginosa isolated from soil, toilets and water. Vitória Bay showed higher frequencies of MDR bacteria and resistance genes, including blaKPC, qnrS, rmtA and rmtG, while in Caramuru only blaTEM and blaCTX-M-1/2 were detected. These results show the diversity and prevalence of resistant bacteria in both rural and urban areas. These results demonstrate the diversity and prevalence of resistant bacteria in rural and urban areas. The detection of MDR bacteria in environments close to human interaction, including water used for irrigation and coastal areas, highlights a significant risk for the spread of antimicrobial resistance. These findings emphasize the urgent need for surveillance and control.
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Prospecção do uso do óleo vegetal da semente de guanandi (Calophyllum brasiliense) como bioinsumo para uso farmacêutico
(Universidade Federal do Espírito Santo, 2024-11-14) Cunha, Gabriel Mendes da; Giuberti, Cristiane dos Santos; https://orcid.org/0000-0002-0560-8731; http://lattes.cnpq.br/3644255863698492; Villanova, Janaína Cecília Oliveira; https://orcid.org/0000-0001-6166-1724; http://lattes.cnpq.br/4226187656439843; https://orcid.org/0000-0003-0548-6110; http://lattes.cnpq.br/2430534515507507; Tavares, Guilherme Diniz; https://orcid.org/0000-0001-6276-0994; http://lattes.cnpq.br/3891648050868116; Severi, Juliana Aparecida; https://orcid.org/0000-0001-7516-2395; http://lattes.cnpq.br/4265400222421660
The guanandi tree (Calophyllum brasiliense) is frequently utilized for reforestation of riparian forests and for obtaining high-quality wood. In recent years, its potential therapeutic benefits have been increasingly investigated. However, to date, there are no reports on the use of guanandi seed vegetable oil (GSGO) as an emollient in pharmaceutical formulations. Emollients are essential for skin hydration, as they form an occlusive barrier that helps retain natural moisture while improving softness and elasticity. The primary objective of this study was to assess the feasibility of using GSGO as an emollient in creams, partially or entirely replacing synthetic emollients such as liquid petrolatum and isopropyl myristate. Initially, the identification of key bioactive components and the physicochemical characterization of GSGO were performed through analyses of pH, spreadability, relative density, optical rotation, acid value, saponification value, and peroxide value. Subsequently, in vitro cytotoxicity and wound healing potential were investigated. Following these analyses, GSGO was incorporated into eight formulations at concentrations of 5% and 10% w/w, replacing synthetic emollients either partially or entirely. The formulations were visually characterized and subjected to thermal and mechanical stress tests for preliminary stability assessment. Among the eight formulations, four showed no signs of alteration. These formulations, containing 10% w/w GSGO, were selected for further study. The selected formulations were stored under different conditions (room temperature, refrigeration, and incubation) for evaluations at 24 hours (T0), 30 days (T1), and 60 days (T2). Macroscopic and microscopic analyses, thermal and mechanical stress tests, heating/cooling cycles, pH measurement, droplet size determination, texture profiling, and occlusive capacity assessments were conducted. Fatty acids accounted for 95% of the lipidic material, with profiles consistent with literature data. The relative density was comparable to other vegetable oils, exhibiting high viscosity and low spreadability. A saponification value close to 200 confirmed the presence of higher molecular weight fatty acids. Cytotoxicity tests indicated no toxic effects on fibroblasts, and the bioactive material promoted cell proliferation and significant reduction of wound area compared to untreated areas. GSGO did not exhibit antimicrobial activity against the tested strains at the applied concentrations. Analysis of the creams revealed stable emulsion systems with a slightly yellowish coloration and increased consistency after 24 hours. Microscopic evaluation showed well-dispersed spherical droplets without aggregation, phase separation, creaming, or flocculation. Based on these findings, one formulation was selected for wound healing research in an animal model, following approval by the Ethics Committee (CEUA protocol 012/2020). The selected formulation, containing 10% w/w GSGO (Anionic Base 2), fully replacing liquid petrolatum and isopropyl myristate, demonstrated wound area contraction in rats comparable to formulations containing allantoin, with and without the bioactive material. These findings support the feasibility of GSGO as an emollient. Overall, the results suggest that cold-pressed, unrefined guanandi seed vegetable oil obtained from naturally fallen fruits in the environment holds promise as a novel bioactive ingredient with emollient properties for pharmaceutical use, exhibiting moisturizing and wound-healing potential.
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Resolução/Cepe/Ufes nº 126, de 4 de julho de 2025
(2025-07-04) Conselho de Ensino, Pesquisa e Extensão
Aprova o Projeto Pedagógico do Curso de Graduação em Estatística e Ciência de Dados – Bacharelado, na modalidade presencial, versão 2026, do Centro de Ciências Exatas da Universidade Federal do Espírito Santo.