Mestrado em Doenças Infecciosas

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http://repositorio.ufes.br/handle/10/17579

Nível: Mestrado Acadêmico
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Navegando Mestrado em Doenças Infecciosas por Autor "Alves, Rosana"

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    Análise do tratamento da infecção latente pelo Mycobacterium tuberculosis na faixa etária de 0 a 15 anos nos programas de referências para tuberculose nos municípios da Grande Vitória/ES-Brasil
    (Universidade Federal do Espírito Santo, 2012-06-29) Gomes, Sandra Mary Jardim; Maciel, Ethel Leonor Noia; Hadad, David Jamil; Miranda, Angelica Espinosa Barbosa; Alves, Rosana
    Controling of Tuberculosis (TB) one of the measures used in Brazil is the treatment of latent infection by Mycobacterium tuberculosis (ILTB), which is made in the TB Control Program (PCT). The evolution of the infection to disease during the life is estimated at 5-10% related to immunocompetent adult, however, in child is estimated 43%.This research was an observational and analytical study, which aimed to analyze the epidemiological profile and factors related to renunciation of treatment for ILTB. Individuals were analyzed until 15 years old who were undergoing treatment for ILTB, in the PCT of the priority municipalities of Vitória, Vila Velha, Serra and Cariacica, which are the sites that used the notification form of treatment for ILTB. The form was used as a tool for data collection. The research period was between July 2009 and August 2010. 144 individuals were found in treatment for ILTB, and 140 (97,22%), the majority of nomination was TB contacts, 46 (31.94%) abandoned the treatment, and 98 (68.06%) completed the treatment. Most individuals were contacts of TB, and when was analyzed the situation of the bacilloscopy (BAAR) of the index case of contact, the majority of both the group that left, and the group that completed treatment, 97,62% e 87,91% (p=0,06), respectively, were positive. Regarding the type of contact, the home was the most frequent, and also between the two groups, both those abandoned and those who completed, totaled 81,82% e 84,21% (p=0,72), respectively, followed by others, who were uncles, grandparents , who lived nearby. Children and teenagers were evaluated mostly had scar of BCG (Bacillus of Calmette and Guérin) present, and had mostly a normal chest X-ray. Teenagers (≥ 10 years old), were checked if they had more chances to leave the treatment of ILTB, comparing with less than 10 years old, because the same need caregivers help for use of medication, however, the majority of both groups, concluded the treatment, teenagers 75% and children 64,13% (p=0.17). This study reinforces the need to control the contacts of patients, identifying priority children and teenagers and developing strategies for treatment adherence. The study can also stimulate the improvement of notification s system since, despite the orientation of MOH, its implementation has not yet been standardized